Zebra danios modified to carry vaccines

5fdac698-bd75-4055-b872-4805bac55f58

Editor's Picks
Practical Fishkeeping Readers' Poll 2023
Fishkeeping News Post
Readers' Poll 2023
07 August 2023
Fishkeeping News Post
Countdown for Finest Fest 2023
20 April 2023
Fishkeeping News Post
Pacific Garbage Patch becomes its own ecosystem
20 April 2023
Fishkeeping News Post
Newly described snails may already be extinct
20 April 2023


Dr Zhiyuan Gong from the National University of Singapore has developed genetically modified Zebra danios that produce vaccines in their muscle tissue.

The scientist, who is best known for his work on producing transgenic danios which glow in the dark, placed non-danio genes into the fish so they produce a vaccine for hepatatis B.

During his work on producing transgenic danios, Dr Gong found that the fish produced large amounts of the protein encoded by a gene inserted from the genetic material of a jellyfish.

Previous work on using transgenic animals to produce vaccines has not been that successful since the amount of protein produced has not been high enough. It is hoped that the Danio will produce similarly large quantities of vaccine protein.